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A total of 703 swine sera from 55 swine farms (Mar. 1998 through Feb. 2001) were nation-wide collected for the presence of the antibody to influenza A virus H3 subtype isolate. The presence of antibody was tested by hemagglutination inhibition with chicken red blood cells and seropositiveness was determined by HI titer ≥1: 40. Sero-prevalence was evaluated based on year, season, region and age, respectively. In consequence, there were some differences by year, season and region, respectively. High susceptibility was routinely observed in 60 and 90 day-old piglets. Therefore, it seems that the sero-prevalence to swine influenza virus H3 subtype isolate is useful for the prevention and control of swine influenza in Korea.
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